基本信息：


基因名

CD82

别名：

KAI1;SAR2;ST6;TSPAN27

蛋白号

P27701

种属

Human

宿主

E.coli

产品描述

Recombinant Human CD82 protein (Antigen) is produced by our E.coli expression system and the target gene encoding 111-220aa is expressed with a N-6His tag.

区间范围

111-220aa

标签信息

N-6His

预测分子量：

11.99 kDa

表观分子量：

12 kDa

纯度

≥85% by SDS-PAGE.

内毒素

Not measured

溶剂

Lyophilized from a 0.45μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, PH7.2-8.0.

复溶

Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml.

储存条件：

Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state.

运输条件：

冷冻运输

背景说明：

CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

细胞活性

Non-active.

ELISA活性

No activity experimental data, to be verified.

SPR/BLI活性

No activity experimental data, to be verified.

研究领域

生物制药相关研究

英文名称：

CD82

中文名称：

CD82蛋白

CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1 suppresses EMT in prostate cancer cells adhered to fibronectin leading to reduced cell migration and invasiveness. CD82/Kai-1 function is important for muscle stem cell function in muscular disorders. Overexpression of CD82/Kai-1 suppresses growth, migration and invasion of oral cancer cells and may be considered as a potential therapeutic target in oral cancer.

细胞活性

Non-active.

ELISA活性

No activity experimental data, to be verified.

SPR/BLI活性

No activity experimental data, to be verified.

研究领域

生物制药相关研究
注意事项：
1.本产品仅供科研使用，请勿用于医药、临床治疗、食品及化收品等用途 。
2.为了您的安全和健康，请穿实验服，口罩，护目镜，并戴一次性手套操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
4.请勿存放于普通住宅区。

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