基本信息：

中文名称：

ActivAbTMMAPK8/MAPK9/MAPK10 抗体封闭肽

英文名称：

ActivAbTMMAPK8/MAPK9/MAPK10 Antibody Blocking Peptide

别名：

C Jun kinase 2,c Jun N terminal kinase 1,c Jun N terminal kinase 2,c Jun N terminal kinase 3,c-Jun N-terminal kinase 1,JNK 46,JNK 55,JNK,JNK-46,JNK1,JNK1A2,JNK2,JNK21B1/2,JNK2A,JNK2ALPHA,JNK2B,JNK2BETA,JNK3 alpha protein kinase,JNK3,JNK3A,Jun kinase,JUN N terminal kinase,MAP kinase 10,MAP kinase 8,MAP kinase 9,MAP kinase p49 3F12,MAPK 10,MAPK 8,MAPK 9,MAPK10,mapk8,MAPK9,Mitogen activated protein kinase 10,Mitogen activated protein kinase 8,Mitogen activated protein kinase 8 isoform JNK1 alpha1,Mitogen activated protein kinase 8 isoform JNK1 beta2,Mitogen activated protein kinase 9,Mitogen-activated protein kinase 8,MK08_HUMAN,p493F12,p54a,p54aSAPK,p54bSAPK,PRKM10,PRKM8,PRKM9,SAPK,SAPK(beta),SAPK1,SAPK1a,SAPK1b,SAPK1c,Stress activated protein kinase 1,Stress activated protein kinase 1a,Stress activated protein kinase 1b,Stress activated protein kinase 1c,Stress activated protein kinase beta,Stress activated protein kinase JNK1,Stress activated protein kinase JNK2,Stress activated protein kinase JNK3,Stress-activated protein kinase 1c,Stress-activated protein kinase JNK1,c Jun kinase 2,C Jun N terminal kinase 2,c-Jun N-terminal kinase 2,JNK 55,JNK-55,JNK2 alpha,JNK2,JNK2 beta,JNK2A,JNK2alpha,JNK2B,JNK2BETA,Jun kinase,MAP kinase 9,MAPK 9,Mapk9,Mitogen activated protein kinase 9,Mitogen-activated protein kinase 9,MK09_HUMAN,P54a,p54aSAPK,PRKM9,Protein kinase,mitogen-activated,9,SAPK alpha,SAPK,SAPK1a,Stress activated protein kinase 1a,Stress-activated protein kinase JNK2,c Jun kinase 3,c-Jun N-terminal kinase 3,cJun N terminal kinase 3,FLJ12099,FLJ33785,JNK3 alpha protein kinase,JNK3,JNK3A,MAP kinase 10,MAP kinase,MAP kinase p49 3F12,MAPK 10,Mapk10,MGC50974,mitogen activated protein kinase 10,Mitogen-activated protein kinase 10,MK10_HUMAN,p493F12,p54bSAPK,PRKM10,protein kinase mitogen activated 10,SAPK1b,Stress activated protein kinase 1b,stress activated protein kinase beta,Stress activated protein kinase JNK3,Stress-activated protein kinase JNK3

外观(性状)：

Lyophilized powder

来源：

Synthetic

储存条件：

Store at -20°C. Avoid freeze / thaw cycles.

运输条件：

冷冻运输

规格：

500ug



生物活性：

应用：

Blocking Peptide of K110326P Antibody

纯化方法：

HPLC

背景说明：

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.

生物活性：

Not tested

该产品为 MAPK8/MAPK9/MAPK10 抗体的抗原肽，在抗体检测、纯化时作为封闭肽使用，对应抗体货号为：K110326P。
抗体封闭肽是一类专门用于免疫学检测体系的功能性合成多肽，其核心作用是通过特异性结合干扰性抗体或非特异性结合位点，从而降低实验背景信号，提高检测结果的准确性和可靠性。它并不直接识别目标抗原，而是充当一种“分子屏蔽层”，封闭那些可能导致假阳性或假阴性结果的非特异性相互作用。
在功能层面，抗体封闭肽主要具备两大特性。一是高亲和力的特异性中和能力——其氨基酸序列与检测体系中可能引起交叉反应的抗体表位完全相同或高度同源，因此能够优先与这些干扰抗体结合，占据其活性位点。二是物理屏蔽作用，即在不干扰靶标抗原与检测抗体正常识别的前提下，封闭固相载体或捕获分子上的空缺结合区域，减少杂蛋白或杂抗体的非特异性吸附。
在应用层面，抗体封闭肽广泛应用于各类免疫分析技术中，包括酶联免疫吸附测定、蛋白质印迹、免疫组化以及免疫层析试纸条等。在自身抗体检测、生物制剂的免疫原性分析以及多重免疫检测方法开发中，它能够有效消除由异嗜性抗体、抗物种抗体或样本基质效应引起的背景干扰。此外，在基于标签融合蛋白的表达检测以及抗体亲和纯化流程中，封闭肽同样扮演着关键角色，可作为竞争性洗脱剂或信号校正控制组使用。
注意事项：
1.本产品仅供科研使用，请勿用于医药、临床治疗、食品及化收品等用途 。
2.为了您的安全和健康，请穿实验服，口罩，护目镜，并戴一次性手套操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。
4.请勿存放于普通住宅区。

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